Stefano Del Prato

Data e luogo di nascita:13/06/1952, Brembate (BG).

Studi eseguiti

- Università di Padova: laurea in medicina (1978)

- Università di Padova: specializzazione in Endocrinologia (1985)

- Università di Padova: specializzazione in Medicina interna (1987)

Esperienza professionale e di ricerca

1978-79: tirocinio, Facoltà di Medicina - Università di Padova

1979-81: medico interno in Medicina Interna, Università di Padova

1983-85 Borsista post-dottorato in Endocrinologia - Yale university, New Haven, CT (USA)

Incarichi accademici

1982-1992 Professore a contratto di Malattie Metaboliche, Ospedale generale di Padova

1984-2000 Professore di "Fisiopatologia del Diabete Mellito" presso la Scuola di Specializzazione in Diabetologia, Università di Padova

1988-1990 Associate Professor- University of Texas - Health Science Center at San Antonio, San Antonio, TX (USA)

1990-ad oggi Clinical associate Professor of Medicine - University of Texas - Health Science Center at San Antonio, San Antonio, TX (USA)

1992-2000 Professore Associato di Malattie Metaboliche, Università di Padova

2000-ad oggi Professore Associato di Malattie Metaboliche, Università di Pisa

2000- ad oggi Direttore del Centro regionale di Riferimento per il Diabete dell'Adulto - Azienda Opedaliera Pisana, Ospedale di Cisanello, Pisa

Premi

1981 Milano Diabetes Prize

1983 Borsa di ricerca "Technologic Research' of the Italian National Research Council at the Yale University, New Haven, CT, USA

1984 borsista N.A.T.O. Yale University, New Haven, CT, USA

1997 Premio della Società Italiana di Diabetologia per le ricerche nel settore diabetologico

PUBLICAZIONII SCIENTIFICHE

DEL PRATO S., NOSADINI R., TIENGO A., TESSARI P., AVOGARO A., TREVISAN R., VALERIO A., MUGGEO M., COBELLI C., TOFFOLO G. Insulin-mediated glucose disposal in type 1 diabetes: evidence for insulin resistance. J. Clin. Endocrinol. Metab. 57:904-910, 1983. (4.002)

Del PRATO s., Vigili de kreutzenberg s., TREVISAN R., DUNER E., AVOGARO A., NOSADINI R., BACCAGLINI U., TREMOLADA C., TIENGO A. Hyperalaninaemia is an early feature of diabetes secondary to total pancreatectomy. Diabetologia 28:277-281, 1985. (4.525)

TREVISAN R., NOSADINI R., AVOGARO A., LIPPE G., DUNER E., FIORETTO P., DEANA R., TESSARI P., TIENGO A., VELUSSI M., CERNIGOI A., DEL PRATO S., CREPALDI G. Type 1 diabetes is characterized by insulin resistance not only with regard to glucose, but also to lipid and amino acid metabolism. J. Clin. Endocrinol. Metab. 62:1155-1162, 1986. (4.002)

DEL PRATO S., CASTELLINO P., SIMONSON D.C., DE FRONZO R.A. Hyperglucagonemia and insulin-mediated glucose metabolism. J. Clin. Invest. 79:136-146, 1987. (8.788)

SIMONSON D.C., DEL PRATO S., CASTELLINO P., GROOP L., DE FRONZO R.A. Effect of glyburide on glucose control, insulin requirement, and glucose metabolism in insulin-treated diabetic patients. Diabetes 36:136-146, 1987. (6.248)

GROOP L.C., BONADONNA R.C., DEL PRATO S., RATHEISER K., ZICK K., FERRANNINI E., DE FRONZO R.A. Glucose and free-fatty acid metabolism in non-insulin-dependent diabetes: evidence for multiple insulin resistance. J. Clin. Invest. 84:205-213, 1989. (8.788)

DEL PRATO S., ENZI G., VIGILI DE KREUTZENBERG S., LISATO G., RICCIO A., MAIFRENI L., IORI E., ZURLO F., SERGI G., TIENGO A. Insulin regulation of glucose and lipid metabolism in massive obesity. Diabetologia 33:228-236, 1990. (4.525)

DEL PRATO S., DE FRONZO R.A., CASTELLINO P., WAHREN J., ALVESTRAND A. Regulation of amino acid metabolism by epinephrine. Am. J. Physiol. 258:E878-E-887, 1990. (3.244)

Vigili de kreutzenberg s., maifreni l., lisato g., riccio a., trevisan r., tiengo a., DEL PRATO S. Glucose turnover and recycling in diabetes secondary to total pancreatectomy: effect of glucagon infusion. J. Clin. Endocrinol. Metab. 70:1023-1029, 1990. (4.002)

GROOP L.C., BONADONNA R.C., DEL PRATO S., RATHEISER K., DE FRONZO R.A. Effect of prolonged overnight fasting on energy metabolism in non-insulin-dependent diabetic and non-diabetic subjects. Acta Endocrinol. 123:30-36, 1990. (2.241)

DEL PRATO S., VIGILI DE KREUTZENBERG S., RICCIO A., MAIFRENI L., DUNER E., LISATO G., IAVICOLI M., TIENGO A. Partial recovery of insulin secretion and action after combined insulin-sulfonylurea treatment in Type 2 (non-insulin-dependent) diabetic patients with secondary failure to oral agents. Diabetologia 33:688-695, 1990. (4.525)

DEL PRATO S. Rationale for combined insulin and sulfonylurea treatment. Am. J. Med. 90 (6A): 77S-82S, 1991 (3.749)

DEL PRATO S., VIGILI DE KREUTZENBERG S., RICCIO A., TIENGO A. Hepatic sensitivity to insulin. Effects of sulfonylurea drugs. Am. J. Med. 90 (6A): 29S-36S, 1991 (3.749)

BONORA E., DEL PRATO S., BONADONNA R.C., GULLI G., SOLINI A., SHANK M.L., GHIATAS A.A, LANCASTER J.L., KILCOYNE R.F., DE FRONZO R.A. Total body fat content and fat topography are differently associated with in vivo glucose metabolism in nonobese and obese nondiabetic women. Diabetes: 41:1120-1127, 1992. (6.248)

DEL PRATO S., RICCIO A., VIGILI DE KREUTZENBERG S., DORELLA M., AVOGARO A., MARESCOTTI M.C., TIENGO A. Mechanisms of fasting hypoglycemia and concomitant insulin resistance in insulinoma patients. Metabolism: 42: 24-29, 1993 (1.807)

DEL PRATO S., BONADONNA R.C., BONORA E., GULLI G., SOLINI A., SHANK M., DE FRONZO R.A. Characterization of cellular defects of insulin action in Type 2 (non-insulin-dependent) diabetes mellitus. J. Clin. Invest.: 91: 484-494, 1993 (8.788)

BONORA E., BONADONNA R.C., DEL PRATO S., GULLI G., MATSUDA M., SOLINI A., DE FRONZO R.A. In vivo glucose metabolism in obese and type II diabetic subjects with or without hypertension. Diabetes: 42:764-772, 1993. (6.248)

BONADONNA R.C., DEL PRATO S., COBELLI C., SACCOMANI M.P., BONORA E., GULLI G., FERRANNINI E., BIER D., DE FRONZO R.A. Transmembrane glucose transport in skeletal muscle of patients with non-insulin dependent diabetes. J. Clin. Invest.: 92:486-494, 1993 (8.788)

FERRANNINI E., NATALI A., BRANDI L.S., BONADONNA R., VIGILI DE KREUTZENBERG S., DEL PRATO S., SANTORO D. Metabolic and thermogenic effects of lactate infusion in humans. Am. J. Physiol. 265:E504-E512, 1993. (3.244)

BONADONNA R.C., DEL PRATO S., BONORA E., GULLI G., SOLINI A., DE FRONZO R.A. Effects of physiologic hyperinsulinemia on the intracellular metabolic partition of plasma glucose. Am. J. Physiol. 265: E943-E953, 1993. (3.244)

RICCIO A., AVOGARO A., VALERIO A., ZAPPELLA A., TIENGO A., DEL PRATO S. Improvement of basal hepatic glucose production and fasting hyperglycemia of type 1 diabetic patients treated with human recombinant ultralente insulin. Diabetes Care: 17: 535-540, 1994 (2.526)

DEL PRATO S., LEONETTI F., SIMONSON D.C., SHEEAN P., DE FRONZO R.A. Effect of chronic physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man. Diabetologia: 37: 1025-1935, 1994 (4.525)

SHANK L.M., DEL PRATO S., DE FRONZO R.A. Bedtime insulin-daytime glipizide: effective therapy for sulfonylurea failures in NIDDM. Diabetes: 44:165-172, 1995 (6.248)

BONORA E., DEL PRATO S., BONADONNA R., GULLI G., SOLINI A., DE FRONZO R.A. Insulin sensitivity is not impaired in mexican-american women without family history of diabetes mellitus. Diabetes Care 18:825-833,1995 (2.526)

DEL PRATO S., RICCIO A., VIGILI DE KREUTZENBERG S., DORELLA M., TIENGO A., DE FRONZO R.A. Basal plasma insulin level plays a qualitative but not a quantitative effect on glucose-mediated glucose metabolism. Am. J. Physiol. 268: E1089-E1095,1995 (3.244)

DEL PRATO S., POZZILLI P. Fasting or false insulin resistance index? Lancet, 347:132, 1996 (17.490)

DORELLA M., GIUSTO M., DA TOS V., CAMPAGNOLO M., PALATINI P., ROSSI G.P., CEOLOTTO G., FELICE M., SEMPLICINI A., DEL PRATO S. Improvement of insulin sensitivity by metformin treatment does not lower blood presure of non-obese insulin-resistant hypertensive patients with normal glucose tolerance. J. Clin. Endocrinol. Metab. 81:1568-1574, 1996 (4.002)

AVOGARO A., MIOLA M., VALERIO A., TOFFOLO G., COBELLI C., TIENGO A., DEL PRATO S. Intracellular lactate- pyruvate-interconversion rates are increased in muscle tissue of non-insulin dependent diabetic individuals. J. Clin Invest. 98:108-115, 1996 (8.788)

BONADONNA R.C., DEL PRATO S., BONORA E., SACCOMANI M.P., GULLI G., NATALI A., FRASCERRA S., PECORI N., FERRANNINI E., BIER D., COBELLI C., DEFRONZO R.A. Roles of glucose transport and glucose phosphorilation in muscle inulin resistance of type 2 (non-insulin dependent) diabetes mellitus. Diabetes, 45:915-925,1996 (6.248)

RICCIO A., LISATO G., VIGILI DE KREUTZENBERG S., MAIFRENI L., TURRIN M., TIENGO A., DEL PRATO S. Gliclazide exerts a specific action on the liver of non-insulin-dependent diabetic patients. Metabolism, 45:1196-1202, 1996 (1.807)

DEL PRATO S., MATSUDA M., SIMONSON D.C., GROOP L., SHEEHAN P., BONADONNA R.C., LEONETTI F., DEFRONZO R.A. Studies on the mass action effect of glucose in NIDDM and IDDM: evidence for glucose resistance. Diabetologia.: 40:687-607, 1997 (4.525)

AVOGARO A., PIARULLI F., VALERIO A., MIOLA M., CALVER M., PAVAN P., COBELLI C., TIENGO A., CALO' L., DEL PRATO S. Forearm nitric oxide balance, vascular relaxation, and glucose metabolism in non-insulin dependent diabetic patients. Diabetes, 41:1040-1046, 1997 (6.248)

BONADONNA R.C., SACCOMANI M.P., DEL PRATO S., BONORA E., DEFRONZO R.A., COBELLI C. Role of tissue specific blood flow and tissue recruitment in insulin-mediated glucose uptake of human skeletal muscle. Circulation, 98: 234-241, 1998

TREVISAN R., BRUTTOMESSO D., VEDOVATO M., BROCCO S., PIANTA A., MAZZON C., JORI E., SEMPLICINI A., TIENGO A., DEL PRATO S. Enhanced responsiveness of blood pressure to sodium intake and to angiotensin II is associated with insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Diabetes, 47: 1347-1353, 1998

AVOGARO A., CALÒ L., PIARULLI F., MIOLA M., DEKREUTZENBERG S., MARAN A., BURLINA A., MINGARDI R., TIENGO A., DEL PRATO S. Effect of Acute Ketosis on the Endothelial Function of Type 1 Diabetic Patients The Role of Nitric Oxide Diabetes 48:391–397, 1999

BRUTTOMESSO D, PIANTA A, MARI A, VALERIO A, MARESCOTTI M-C, AVOGARO A, TIENGO A, DEL PRATO S. Restoration of early rise in plasma insulin levels improves the glucose tolerance of Type 2 diabetic patients. Diabetes, 48:99-105, 1999

MARAN A., CREPALDI C., TRUPIANI S., LUCCA T., JORI E., MACDONALD I.A., TIENGO A., AVOGARO A., DEL PRATO S. Brain function rescue effect of lactate following hypoglicaemia is not an adaptation process both in normal and type 1 diabetic individuals. Diabetologia, 43:733-741, 2000

DE KREUTZENBERG S, CREPALDI C, MARCHETTO S, CALO L, TIENGO A, DEL PRATO S, AVOGARO A Plasma free-fatty acids and endothelium dependent vasodilation: effect of chain-lenght and cyclooxygenase inhibition. J Clin Endocrinol Metab 85:793-798, 2000

MONUANI T, ZENTI MG, CRETTI A, DANIELS MC, TARGHER G, CARUSO B, CAPUTO M, MCCLAIN D, DEL PRATO S, GIACCARI A., MUGGEO M, BONORA E, BONADONNA R.C. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes 49:926-935, 2000

VIGILI DE KREUTZENBERG, DEL PRATO S. Left ventricular mass in non-insulin-dependent mellitus. A study employing a simple ECG index: the Cornell voltage. J Endocrinol Invest, 23:134-144, 2000 (0.906)

BALDEWEG S.E., GOLAY A., NATALI A., BALKAU B., DEL PRATO S., COPPACK S.W. on behalf of EGIR (European Group for the Study of Insulin Tresistance). Insulin resistance, non-esterified fatty acids and lipoprotein concentrations: relationship seen in a cohort of 867 non-diabetic European subjects. Eur. J. Clin. Invest,30:45-52, 2000

BRUTTOMESSO D, FONGHER C, SILVESTRI B, BARBERIO S, MARESCOTTI MC, IORI E, VALERIO A, CRAZZOLARA D, PIANTA A, TIENGO A, DEL PRATO S. Combination of continuous subcutaneous infusion of insulin and octreotide in Type 1 diabetic patients.Diab Res Clin Pract 51:97-105, 2001

C o n t e n u t o   d e l   s i t o
NOVITA' | FORMAZIONE E DIDATTICA |
RICERCA | CLINICA | LINKS | POSTA | HOME

Realizzazione grafica e contenuti: Dott. R. Miccoli, Valentina Lamorgese, Paolo Novelli